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A Phase I/II study of the tumor-targeting human L19IL2 monoclonal antibody-cytokine fusion protein in combination with Rituximab in relapsed or refractory Diffuse Large B-cell Lymphoma (DLBCL)

Trial Profile

A Phase I/II study of the tumor-targeting human L19IL2 monoclonal antibody-cytokine fusion protein in combination with Rituximab in relapsed or refractory Diffuse Large B-cell Lymphoma (DLBCL)

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 12 Oct 2023

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At a glance

  • Drugs Bifikafusp alfa (Primary) ; Rituximab
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Philogen
  • Most Recent Events

    • 06 Oct 2023 Status changed from active, no longer recruiting to discontinued. Slow progression due to difficulties in finding eligible patients. Competitive clinical trials with innovative agents and new approved products lead definitive stop.
    • 06 Oct 2023 This study has been discontinued in Germany, according to European Clinical Trials Database record.
    • 19 Apr 2022 Planned End Date changed from 1 Dec 2019 to 1 Dec 2022.

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