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A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation

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Trial Profile

A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Sep 2024

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At a glance

  • Drugs Vorasidenib (Primary)
  • Indications Glioma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Agios Pharmaceuticals

Most Recent Events

  • 22 Jul 2024 Status changed from active, no longer recruiting to completed.
  • 21 Mar 2024 Planned End Date changed from 1 Dec 2023 to 1 Mar 2024.
  • 07 Aug 2023 Planned End Date changed from 1 Jun 2023 to 1 Dec 2023.

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