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Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals With Irradiation-Induced Parotid Salivary Hypofunction

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Trial Profile

Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals With Irradiation-Induced Parotid Salivary Hypofunction

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 22 Aug 2023

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At a glance

  • Drugs AAV AQP1 (Primary)
  • Indications Head and neck cancer; Squamous cell cancer; Xerostomia
  • Focus Adverse reactions; Proof of concept
  • Sponsors MeiraGTx

Most Recent Events

  • 16 Aug 2023 Status changed from recruiting to active, no longer recruiting.
  • 08 Jun 2023 Planned number of patients changed from 36 to 21.
  • 08 Jun 2023 Planned End Date changed from 1 Jul 2025 to 1 Jul 2026.

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