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A Phase I Clinical Trial of Combined Cryotherapy and Intra-tumoral Immunotherapy With Autologous Immature Dendritic Cells in Men With Castration Resistant Prostatic Cancer and Metastases to Lymph Nodes and/or Bone Pre or Post Chemotherapy

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Trial Profile

A Phase I Clinical Trial of Combined Cryotherapy and Intra-tumoral Immunotherapy With Autologous Immature Dendritic Cells in Men With Castration Resistant Prostatic Cancer and Metastases to Lymph Nodes and/or Bone Pre or Post Chemotherapy

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Jul 2023

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At a glance

  • Drugs ACT 2001 (Primary) ; Cyclophosphamide; Ipilimumab; Pembrolizumab
  • Indications Prostate cancer
  • Focus Adverse reactions; Pharmacodynamics
  • Acronyms CryoIT
  • Sponsors Alden Cancer Therapy II

    • Most Recent Events

    • 06 Jun 2023 Results assessing safety and immune response dendritic cell based cryoimmunotherapy combined with checkpoint inhibitors in mCRPC presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 26 Jul 2020 Second interim results presented at the 35th Congress of the European Association of Urology
    • 31 May 2020 Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology

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