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A Randomised, Double-blind, Double-dummy, Placebo-controlled, Parallel-group Multi-centre Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function

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Trial Profile

A Randomised, Double-blind, Double-dummy, Placebo-controlled, Parallel-group Multi-centre Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 Dec 2021

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At a glance

  • Drugs Anti-interleukin-21 monoclonal antibody (Primary) ; Liraglutide (Primary)
  • Indications Type 1 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Novo Nordisk
  • Most Recent Events

    • 25 Sep 2020 Primary endpoint has been met. (Area under the curve (AUC)0-4h mixed meal tolerance test(MMTT) stimulated C-peptide concentration-time curve)
    • 25 Sep 2020 Results presented at the 56th Annual Meeting of the European Association for the Study of Diabetes
    • 16 Jun 2020 Results presented at the 80th Annual Scientific Sessions of the American Diabetes Association

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