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A Phase II Study of the Combination of LY3023414 and Necitumumab After First-Line Chemotherapy for Metastatic Squamous Non-small Cell Carcinoma of the Lung

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Trial Profile

A Phase II Study of the Combination of LY3023414 and Necitumumab After First-Line Chemotherapy for Metastatic Squamous Non-small Cell Carcinoma of the Lung

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 11 Dec 2020

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At a glance

  • Drugs Samotolisib (Primary) ; Necitumumab
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus First in man; Therapeutic Use
  • Sponsors Eli Lilly and Company
  • Most Recent Events

    • 15 May 2018 Status changed to discontinued due to lack of activity as the observed DCR at 6 months is 4%, below the hypothesized 44% DCR at 6 months as the primary objective of this study.
    • 26 Jul 2017 Planned End Date changed from 1 Jul 2017 to 1 Sep 2017.
    • 26 Jul 2017 Planned primary completion date changed from 1 Jul 2017 to 1 Sep 2017.

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