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Adapalene vs. Placebo as Prophylaxis for anti-EGFRs-induced Acne-like rash, a Randomized left-right Comparative Evaluation (APPEARANCE)

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Trial Profile

Adapalene vs. Placebo as Prophylaxis for anti-EGFRs-induced Acne-like rash, a Randomized left-right Comparative Evaluation (APPEARANCE)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 26 Dec 2019

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At a glance

  • Drugs Adapalene (Primary) ; Minocycline
  • Indications Acne
  • Focus Therapeutic Use
  • Acronyms APPEARANCE

Most Recent Events

  • 05 Jun 2018 Primary endpoint (The difference in total facial lesion count of acne-like rash at 4 weeks) has not been met, as per the results presented at the 54th Annual Meeting of the American Society of Clinical Oncology
  • 05 Jun 2018 Results (n=26) evaluating the prophylactic efficacy presented at the 54th Annual Meeting of the American Society of Clinical Oncology
  • 06 Mar 2018 Status changed from active, no longer recruiting to completed.

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