A Phase 1b Dose Escalation and Dose Expansion Study of Tirabrutinib (ONO/GS-4059) in Combination With Other Targeted Anti-cancer Therapies in Subjects With B-cell Malignancies
Latest Information Update: 18 Oct 2024
At a glance
- Drugs Tirabrutinib (Primary) ; Entospletinib; Idelalisib; Obinutuzumab
- Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
- Focus Adverse reactions; Therapeutic Use
- Sponsors Gilead Sciences
Most Recent Events
- 11 Oct 2024 Status changed from active, no longer recruiting to discontinued.
- 01 Jul 2024 Planned End Date changed from 1 Dec 2025 to 1 Dec 2024.
- 01 Jul 2024 Planned primary completion date changed from 1 Dec 2025 to 1 Dec 2024.