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FOCUS: A Multicenter, Multinational, Double-Blind, 2-Arm, Randomized, Phase 2/3, Study of Physician's Choice Chemotherapy ([PCC] Weekly Paclitaxel or Pegylated Liposomal Doxorubicin [PLD]) Plus Bevacizumab and CA4P Versus PCC Plus Bevacizumab and Placebo for Subjects With Platinum-Resistant, Recurrent Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer

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Trial Profile

FOCUS: A Multicenter, Multinational, Double-Blind, 2-Arm, Randomized, Phase 2/3, Study of Physician's Choice Chemotherapy ([PCC] Weekly Paclitaxel or Pegylated Liposomal Doxorubicin [PLD]) Plus Bevacizumab and CA4P Versus PCC Plus Bevacizumab and Placebo for Subjects With Platinum-Resistant, Recurrent Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 26 Mar 2025

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At a glance

  • Drugs Bevacizumab (Primary) ; Fosbretabulin (Primary)
  • Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms FOCUS
  • Sponsors Mateon Therapeutics

    • Most Recent Events

    • 26 Sep 2017 Primary endpoint (Progression free survival) has not been met, according to a Mateon Therapeutics media release.
    • 26 Sep 2017 Results presented in a Mateon Therapeutics media release.
    • 26 Sep 2017 According to a Mateon Therapeutics media release, the Company terminated this study due to lack of clear efficacy signal in the third interim analysis.

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