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An Open-label Extension Study of Subcutaneously Administered Fitusiran in Patients With Moderate or Severe Hemophilia A or B Who Have Participated in a Previous Clinical Study With Fitusiran

Trial Profile

An Open-label Extension Study of Subcutaneously Administered Fitusiran in Patients With Moderate or Severe Hemophilia A or B Who Have Participated in a Previous Clinical Study With Fitusiran

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 Jun 2024

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At a glance

  • Drugs Fitusiran (Primary)
  • Indications Haemophilia A; Haemophilia B
  • Focus Adverse reactions
  • Sponsors Alnylam Pharmaceuticals; Sanofi Genzyme

Most Recent Events

  • 12 Dec 2023 Results of pooled analysis from Phase 1 (NCT02035605), Phase 1/2 (NCT02554773) and Phase 3 studies (NCT03417102, NCT03417245, NCT03549871) in PwH A/B, with or without inhibitors, PopPK/PD model, presented at the 65th American Society of Hematology Annual Meeting and Exposition.
  • 03 Apr 2023 Status changed from active, no longer recruiting to completed.
  • 04 Aug 2022 Planned End Date changed from 21 Jun 2023 to 4 Apr 2023.

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