Trial Profile

An Open-Label, Randomized Phase 3 Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum Doublet Chemotherapy Versus Platinum Doublet Chemotherapy in Subjects With Chemotherapy-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC)

Status: Completed

Phase of Trial: Phase III

Latest Information Update: 22 Nov 2024

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At a glance

Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Paclitaxel; Pemetrexed
Indications Brain metastases; Non-small cell lung cancer; Squamous cell cancer
Focus Registrational; Therapeutic Use
Acronyms CheckMate 227
Sponsors Bristol-Myers Squibb; Ono Pharmaceutical

19 Nov 2024 Status changed from active, no longer recruiting to completed.
01 Oct 2024 This trial has been completed in Germany, according to European Clinical Trials Database
01 Oct 2024 This trial has been completed in Poland, according to European Clinical Trials Database .

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