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An Evaluation of Bone Mineral Density in HIV-1-infected Adult Subjects Switching From a Tenofovir-containing Antiretroviral Therapy Regimen to a Dolutegravir Plus Rilpivirine Regimen

Trial Profile

An Evaluation of Bone Mineral Density in HIV-1-infected Adult Subjects Switching From a Tenofovir-containing Antiretroviral Therapy Regimen to a Dolutegravir Plus Rilpivirine Regimen

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 01 Mar 2024

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At a glance

  • Drugs Dolutegravir/rilpivirine (Primary)
  • Indications HIV-1 infections
  • Focus Pharmacodynamics; Registrational
  • Sponsors ViiV Healthcare

Most Recent Events

  • 08 Nov 2018 Status changed from active, no longer recruiting to completed.
  • 23 May 2018 Results assessing health outcoms by using data from three studies (SWORD-1, SWORD-2 and DEXA sub-study) presented at the 23rd Annual International Meeting of the International Society for Pharmacoeconomics and Outcomes Research.
  • 12 Dec 2017 Results assessing changes at Week 48 in BMD after switching from a three-drug regimen containing tenofovir disoproxil fumarate to the NRTI-sparing dolutegravir+rilpivirine regimen, were published in the AIDS.

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