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A Phase 1, Randomized, Double Blind, Sponsor Open, Placebo Controlled, Sequential Group, Multiple Ascending Dose Escalation Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Orally Administered Pf 06650833 In Healthy Subjects

Trial Profile

A Phase 1, Randomized, Double Blind, Sponsor Open, Placebo Controlled, Sequential Group, Multiple Ascending Dose Escalation Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Orally Administered Pf 06650833 In Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Zimlovisertib (Primary) ; Zimlovisertib (Primary)
  • Indications Lupus nephritis; Lupus vulgaris; Lupus-like syndrome
  • Focus Adverse reactions
  • Sponsors Pfizer
  • Most Recent Events

    • 23 Aug 2021 Results of PF-06650833 demonstrated in-vivo pharmacology pertinent to systemic lupus erythematosus by reducing whole blood interferon gene signature expression in healthy volunteers, published in the Arthritis and Rheumatology.
    • 06 May 2016 Status changed from active, no longer recruiting to completed.
    • 29 Apr 2016 Status changed from recruiting to active, no longer recruiting.

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