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A Phase I/II, Open-label, Dose-escalating, Sequential-cohort Study Assessing the Safety, Tolerability, Immunogenicity, and Bioactivity of a Single Intravitreal Injection of DE-122 Injectable Solution for the Treatment of Refractory Exudative Age-related Macular Degeneration

Trial Profile

A Phase I/II, Open-label, Dose-escalating, Sequential-cohort Study Assessing the Safety, Tolerability, Immunogenicity, and Bioactivity of a Single Intravitreal Injection of DE-122 Injectable Solution for the Treatment of Refractory Exudative Age-related Macular Degeneration

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 16 Jan 2020

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At a glance

  • Drugs Carotuximab (Primary)
  • Indications Wet age-related macular degeneration
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PAVE
  • Sponsors Santen Inc

Most Recent Events

  • 12 Feb 2018 According to a Santen media release, results were presented at the 15th Annual Angiogenesis, Exudation, and Degeneration, a medical symposium presented by Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine.
  • 12 Feb 2018 Results presented in a Santen media release.
  • 11 Sep 2017 Status changed from active, no longer recruiting to completed.

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