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A Randomized, Open-label, Phase II Study of Maintaining Pan-ERBB Blockade Following Platinum-based Induction Chemotherapy in Patients With EGFR Mutated, Metastatic Non-small-cell Lung Cancer Progressing After Treatment With Afatinib as First EGFR-targeting Agent

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A Randomized, Open-label, Phase II Study of Maintaining Pan-ERBB Blockade Following Platinum-based Induction Chemotherapy in Patients With EGFR Mutated, Metastatic Non-small-cell Lung Cancer Progressing After Treatment With Afatinib as First EGFR-targeting Agent

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Afatinib (Primary) ; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms MARBLE

    • Most Recent Events

    • 08 Jan 2018 Status changed from suspended to discontinued.
    • 02 Dec 2017 Status changed from recruiting to suspended.
    • 16 Nov 2015 Planned End Date changed from 1 Jan 2018 to 1 Apr 2018 as reported by ClinicalTrials.gov.

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