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A Phase 1 Multidose Study to Evaluate the Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-Expressing Hematologic Malignancies

Trial Profile

A Phase 1 Multidose Study to Evaluate the Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-Expressing Hematologic Malignancies

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 12 Feb 2025

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At a glance

  • Drugs Plamotamab (Primary) ; Plamotamab (Primary)
  • Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; First in man
  • Sponsors Xencor

Most Recent Events

  • 06 Nov 2024 According to a Xencor media release, data from subcutaneous dosing cohorts in patients with relapsed or refractory non-Hodgkin's lymphoma will be presented at the 66th American Society of Hematology Annual Meeting.
  • 09 Sep 2024 According to a Xencor media release, company has completed a Phase 1 clinical study of plamotamab in hematologic cancers, completing enrollment in late 2023.
  • 09 Sep 2024 Status changed from active, no longer recruiting to completed, according to a Xencor media release.

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