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A Phase I/II Study of MG1 Maraba/MAGE-A3 (MG1MA3), With and Without Adenovirus Vaccine, With Transgenic MAGE-A3 Insertion (AdMA3) in Patients With Incurable Advanced/Metastatic MAGE-A3-Expressing Solid Tumours

Trial Profile

A Phase I/II Study of MG1 Maraba/MAGE-A3 (MG1MA3), With and Without Adenovirus Vaccine, With Transgenic MAGE-A3 Insertion (AdMA3) in Patients With Incurable Advanced/Metastatic MAGE-A3-Expressing Solid Tumours

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Mar 2025

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At a glance

  • Drugs MG1 MA3 (Primary) ; Ad MAGEA3
  • Indications Adenocarcinoma; Advanced breast cancer; Gastric cancer; Non-small cell lung cancer; Oesophageal cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms LANDMARK

Most Recent Events

  • 11 Mar 2025 Planned End Date changed from 31 Dec 2024 to 31 Dec 2025.
  • 09 Feb 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2024.
  • 03 Aug 2023 Planned End Date changed from 30 Jun 2023 to 31 Dec 2023.

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