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Crizotinib in Pretreated Metastatic Non-small-cell Lung Cancer With MET Amplification or MET Exon 14 Mutation or ROS1 Translocation (METROS)

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Trial Profile

Crizotinib in Pretreated Metastatic Non-small-cell Lung Cancer With MET Amplification or MET Exon 14 Mutation or ROS1 Translocation (METROS)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Sep 2022

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At a glance

  • Drugs Crizotinib (Primary)
  • Indications Brain metastases; Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms METROS

Most Recent Events

  • 09 Aug 2022 Results (n=64) of long-term outcomes analysis of ROS1+ patients with brain metastases (BM). presented at the 2022 World Conference on Lung Cancer
  • 01 Apr 2020 Results (N=10), providing detailed molecular data for the 10 patients with MET exon 14 mutations, published in the Clinical Cancer Research
  • 15 Aug 2019 Results (n=52, data cut off: Sep 2017) investigating activity of crizotinib in patients harboring MET or ROS1 alterations published in the Clinical Cancer Research

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