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Randomized, Double-blind, Phase 3 Study Evaluating TAS-102 Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Patients With Metastatic Gastric Cancer Refractory to Standard Treatments

Trial Profile

Randomized, Double-blind, Phase 3 Study Evaluating TAS-102 Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Patients With Metastatic Gastric Cancer Refractory to Standard Treatments

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 26 Feb 2025

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At a glance

  • Drugs Tipiracil/trifluridine (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms TAGS
  • Sponsors Taiho Oncology
  • Most Recent Events

    • 05 Oct 2023 Results assessing tolerability and safety of Ramucirumab beyond progression plus TAS-102 in patients with advanced or metastatic esophagogastric adenocarcinoma from RE-ExPEL trial compared to historical results from TAGS trial published in the International Journal of Cancer
    • 17 Aug 2023 Results of a post-hoc sub-group analysis assessing impact of prior therapy type on outcomes published in the Journal of Cancer Research and Clinical Oncology
    • 17 Jan 2021 Results of retrospective analysis assessing association of early BWL with survival outcomes presented at the 2021 Gastrointestinal Cancers Symposium

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