Trial Profile

A Phase III Randomized Trial Comparing Physician/Patient Choice of Either High Dose Interferon or Ipilimumab to MK-3475 (Pembrolizumab) in Patients With High Risk Resected Melanoma

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 05 Apr 2026

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At a glance

Drugs Pembrolizumab (Primary) ; Interferon alpha-2b; Interferon alpha-2b; Ipilimumab
Indications Malignant melanoma
Focus Therapeutic Use
Acronyms SWOG 1404

Most Recent Events

03 Mar 2026 Planned End Date changed from 23 Jan 2026 to 23 Jan 2027.
13 Mar 2025 Planned End Date changed from 23 Jan 2025 to 23 Jan 2026.
04 Jun 2024 Results (n=82) of exploratory analysis assessing the association between the presence of ctDNA after definitive surgical resection and RFS in pts with stage III melanoma treated with adjuvant immunotherapy presented at the 60th Annual Meeting of the American Society of Clinical Oncology

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