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A Phase 2, Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Exploratory Study to Evaluate Effects of VX-661 in Combination With Ivacaftor on Lung and Extrapulmonary Systems in Subjects Aged 18 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

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Trial Profile

A Phase 2, Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Exploratory Study to Evaluate Effects of VX-661 in Combination With Ivacaftor on Lung and Extrapulmonary Systems in Subjects Aged 18 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Ivacaftor/tezacaftor (Primary)
  • Indications Cystic fibrosis
  • Focus Therapeutic Use
  • Sponsors Vertex Pharmaceuticals

    • Most Recent Events

    • 04 Jun 2019 According to a Vertex Pharmaceuticals media release, data from this trial will be presented at the 42nd European Cystic Fibrosis Conference (June 5th-8th, 2019 in Liverpool, UK).
    • 08 Aug 2017 Status changed from recruiting to completed.
    • 23 Feb 2017 Planned End Date changed from 1 Jan 2017 to 1 Jul 2017.

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