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A Phase III, Double-blind, Randomized, Placebo-controlled Multi-centre, Study to Assess the Efficacy and Safety of AZD9291 Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Trial Profile

A Phase III, Double-blind, Randomized, Placebo-controlled Multi-centre, Study to Assess the Efficacy and Safety of AZD9291 Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 03 Apr 2025

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At a glance

  • Drugs Osimertinib (Primary)
  • Indications Adenocarcinoma; Adenosquamous carcinoma; Carcinoma; Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ADAURA
  • Sponsors AstraZeneca

Most Recent Events

  • 04 Jun 2024 Results exploring if plasma ctDNA-based, tumor-informed MRD could predict disease recurrence were presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
  • 22 May 2024 According to an AstraZeneca media release, data from this study will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting
  • 20 May 2024 Planned End Date changed from 31 Dec 2030 to 31 Jan 2029.

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