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A Randomized, Double-Blinded, Placebo-Controlled Trial of a Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin, Januvia) for Reducing Inflammation and Immune Activation in HIV-Infected Men and Women: A Multicenter Trial of the AIDS Clinical Trials Group (ACTG)

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Trial Profile

A Randomized, Double-Blinded, Placebo-Controlled Trial of a Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin, Januvia) for Reducing Inflammation and Immune Activation in HIV-Infected Men and Women: A Multicenter Trial of the AIDS Clinical Trials Group (ACTG)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 09 May 2024

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At a glance

  • Drugs Sitagliptin (Primary)
  • Indications Inflammation
  • Focus Therapeutic Use

Most Recent Events

  • 10 Dec 2018 Primary endpoint (Change in sCD14 From Baseline to Week 15/16) has not been met as per results published in the Clinical Infectious Diseases.
  • 10 Dec 2018 Results assessing inflammation and immune markers published in the Clinical Infectious Diseases.
  • 15 Mar 2017 Status changed from active, no longer recruiting to completed.

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