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A Phase I/II Study of Preoperative (Neoadjuvant) Combination of Letrozole (Femara), Everolimus (Afinitor), and TRC105 in Postmenopausal Women With Newly Diagnosed Local or Locally Advanced Potentially Resectable Hormone-Receptor Positive and Her2 Negative Breast Cancer

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Trial Profile

A Phase I/II Study of Preoperative (Neoadjuvant) Combination of Letrozole (Femara), Everolimus (Afinitor), and TRC105 in Postmenopausal Women With Newly Diagnosed Local or Locally Advanced Potentially Resectable Hormone-Receptor Positive and Her2 Negative Breast Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Dec 2024

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At a glance

  • Drugs Carotuximab (Primary) ; Everolimus; Letrozole
  • Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer
  • Focus Adverse reactions

    • Most Recent Events

    • 27 Dec 2024 Planned End Date changed from 1 Dec 2024 to 31 Dec 2026.
    • 27 Dec 2024 Planned primary completion date changed from 1 Dec 2024 to 31 Dec 2025.
    • 27 Dec 2024 Status changed from completed to active, no longer recruiting.

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