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A Phase I, Open Label, Multicenter Study of the Safety and Efficacy of MIW815 (ADU-S100) Administered by Intratumoral Injection to Patients With Advanced/Metastatic Solid Tumors or Lymphomas

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Trial Profile

A Phase I, Open Label, Multicenter Study of the Safety and Efficacy of MIW815 (ADU-S100) Administered by Intratumoral Injection to Patients With Advanced/Metastatic Solid Tumors or Lymphomas

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 03 Jan 2022

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At a glance

  • Drugs ADU-S100 (Primary) ; Ipilimumab (Primary)
  • Indications Advanced breast cancer; Colorectal cancer; Endometrial cancer; Head and neck cancer; Lymphoma; Malignant melanoma; Merkel cell carcinoma; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Parotid cancer; Renal cell carcinoma; Sarcoma; Solid tumours; Uveal melanoma
  • Focus Adverse reactions; First in man
  • Sponsors Aduro BioTech; Chinook Therapeutics; Novartis Pharma A.G.

    • Most Recent Events

    • 10 Dec 2021 Status changed from active, no longer recruiting to discontinued. Reason the study was stopped: No substantial anti-tumor activity was observed.
    • 29 Oct 2021 Results published in the Clinical Cancer Research
    • 08 Jul 2020 Planned End Date changed from 1 Dec 2020 to 1 Feb 2021.

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