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Neoadjuvant and Adjuvant Checkpoint Blockade in Patients With Clinical Stage III or Oligometastatic Stage IV Melanoma

Trial Profile

Neoadjuvant and Adjuvant Checkpoint Blockade in Patients With Clinical Stage III or Oligometastatic Stage IV Melanoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Jan 2025

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Relatlimab (Primary)
  • Indications Acral lentiginous melanoma; Malignant melanoma; Skin cancer; Uveal melanoma
  • Focus Therapeutic Use

Most Recent Events

  • 04 Jun 2024 Results (n=26) assessing gene expression signatures analysis from BL and longitudinal tumor tissues and correlations with outcomes presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 24 Oct 2023 Pooled analysis result of NCT02231775 and NCT02519322 trial assessing relapse free survival at 3 years by pathological response to neoadjuvant systemic treatment in patients with surgically resectable, high-risk melanoma (n=97) presented at the 48th European Society for Medical Oncology Congress.
  • 06 Feb 2023 Status changed from active, no longer recruiting to completed.

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