Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

Trial Profile

Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemia

Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 20 Apr 2018

At a glance

  • Drugs Selinexor (Primary) ; Sorafenib
  • Indications Acute myeloid leukaemia; Chronic myelomonocytic leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions
  • Most Recent Events

    • 12 Feb 2018 Planned End Date changed from 1 Dec 2019 to 1 Dec 2020.
    • 12 Dec 2017 Results (n=14) presented at the 59th Annual Meeting and Exposition of the American Society of Hematology
    • 01 Nov 2017 According to a Karyopharm Therapeutics media release, updated data from this trial will be presented at the American Society of Hematology (ASH) 2017 annual meeting.
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