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A Randomized, Placebo-controlled, Double-blind, Multicenter Phase 2 Study of Atezolizumab With or Without Entinostat in Patients With Advanced Triple Negative Breast Cancer, With a Phase 1b Lead in Phase

Trial Profile

A Randomized, Placebo-controlled, Double-blind, Multicenter Phase 2 Study of Atezolizumab With or Without Entinostat in Patients With Advanced Triple Negative Breast Cancer, With a Phase 1b Lead in Phase

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 06 Dec 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Entinostat (Primary)
  • Indications Advanced breast cancer; Carcinoma; Triple negative breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ENCORE 602
  • Sponsors Syndax Pharmaceuticals
  • Most Recent Events

    • 09 May 2022 Status changed from active, no longer recruiting to completed.
    • 31 May 2020 Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology
    • 07 Mar 2019 Primary endpoint of duration of Progression-free survival has not been met, according to a Syndax Pharmaceuticals media release.

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