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A multicenter, randomized, double-blind, double-dummy, parallel-group, active-controlled study to evaluate the efficacy and safety of finerenone compared to eplerenone on morbidity and mortality in patients with chronic heart failure and reduced ejection fraction after recent heart failure decompensation and additional risk factors, either type 2 diabetes mellitus or chronic kidney disease or both

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A multicenter, randomized, double-blind, double-dummy, parallel-group, active-controlled study to evaluate the efficacy and safety of finerenone compared to eplerenone on morbidity and mortality in patients with chronic heart failure and reduced ejection fraction after recent heart failure decompensation and additional risk factors, either type 2 diabetes mellitus or chronic kidney disease or both

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 12 Dec 2022

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At a glance

  • Drugs Finerenone (Primary) ; Eplerenone
  • Indications Chronic heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms FINESSE-HF
  • Sponsors Bayer; Bayer HealthCare

    • Most Recent Events

    • 15 Jun 2019 Status changed from recruiting to discontinued.
    • 15 Jun 2019 This trial has been discontinued in United Kingdom, according to European Clinical Trials Database.
    • 16 Nov 2018 The trial was prematurely ended in Germany.

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