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A Phase 1 Multi Arm Study Evaluating the Safety, Pharmacology and Preliminary Activity of the Co-Administration of MM-151 With Seribantumab (MM-121), Istiratumab (MM-141), or Trametinib in Biomarker-selected Cancer Patients

Trial Profile

A Phase 1 Multi Arm Study Evaluating the Safety, Pharmacology and Preliminary Activity of the Co-Administration of MM-151 With Seribantumab (MM-121), Istiratumab (MM-141), or Trametinib in Biomarker-selected Cancer Patients

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 03 Oct 2021

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At a glance

  • Drugs Istiratumab (Primary) ; MM-151 (Primary) ; Seribantumab (Primary) ; Trametinib (Primary)
  • Indications Colorectal cancer; Head and neck cancer; Lung cancer; Squamous cell cancer
  • Focus Adverse reactions
  • Sponsors Merrimack Pharmaceuticals

Most Recent Events

  • 31 Aug 2017 Status changed from recruiting to discontinued.
  • 07 Jun 2016 Trial design presented at the 52nd Annual Meeting of the American Society of Clinical Oncology
  • 19 May 2016 Treatment table, drug descriptors and purpose were modified to reflect the changes presented in a Merrimack Pharmaceuticals media release.

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