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Randomized, Double-Blind, Phase III Trial Olaparib vs. Placebo Patients With Advanced FIGO Stage IIIB-IV High Grade Serious or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer Treated Standard First-Line Treatment

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Randomized, Double-Blind, Phase III Trial Olaparib vs. Placebo Patients With Advanced FIGO Stage IIIB-IV High Grade Serious or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer Treated Standard First-Line Treatment

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 25 Oct 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Olaparib (Primary) ; Antineoplastics
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms PAOLA-1; PAOLA-1/ENGOT-ov25

    • Most Recent Events

    • 01 Nov 2023 Results published in the Oncogene
    • 06 Jun 2023 Results of PAOLA-1 ancillary study assessing BRCA1 and RAD51C methylation analysis were presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
    • 06 Jun 2023 Results assessing Blinded-assessment of a solution to evaluate olaparib maintenance treatment efficacy in patients with ovarian cancer from the GINECO/ENGOT PAOLA-1 trial, presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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