Randomized Phase IB/II Study of Enzalutamide With and Without Ribociclib in Patients With Metastatic Castrate Resistant, Chemotherapy Naïve Prostate Cancer That Retains RB Expression
Phase of Trial: Phase I/II
Latest Information Update: 16 Feb 2018
At a glance
- Drugs Ribociclib (Primary) ; Enzalutamide
- Indications Prostate cancer
- Focus Adverse reactions; Therapeutic Use
- 16 Feb 2018 According to trial design presented at the 2018 Genitourinary Cancers Symposium, dose levels 1 and 2 have been completed without any DLTs in the phase I portion and a review was planned for dose level 3 in Oct 2017.
- 16 Feb 2018 Trial design presented at the 2018 Genitourinary Cancers Symposium.
- 28 Nov 2017 Planned primary completion date changed from 1 Sep 2020 to 14 Apr 2020.