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A multicenter randomized 52 week treatment double-blind, triple-dummy parallel-group study to assess the efficacy and safety of QMF149 compared with mometasone furoate in patients with asthma

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Trial Profile

A multicenter randomized 52 week treatment double-blind, triple-dummy parallel-group study to assess the efficacy and safety of QMF149 compared with mometasone furoate in patients with asthma

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 Jul 2022

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At a glance

  • Drugs Indacaterol/mometasone (Primary) ; Mometasone; Salmeterol/fluticasone propionate
  • Indications Asthma
  • Focus Registrational; Therapeutic Use
  • Acronyms PALLADIUM
  • Sponsors Novartis; Novartis Pharma A.G.; Novartis Pharma KK; Novartis Pharmaceuticals

Most Recent Events

  • 25 Jul 2022 Results of post-hoc analysis assessing efficacy and safety of IND/MF versus SAL/FLU in Asian patients with inadequately controlled asthma from two (PALLADIUM and IRIDIUM) published in the Journal of Asthma
  • 24 Jan 2022 A review outlining the unique strategy used in the accelerated development of IND/GLY/MF that combined various approaches comprising data from 3 study (QUARTZ and PALLADIUM evaluated IND/MF while IRIDIUM and ARGON evaluated IND/GLY/MF) published in the Advances in Therapy
  • 22 May 2021 Results (n=698) of pooled analysis from 2 trials (PALLADIUM and IRIDIUM) assessing the population pharmacokinetic (popPK) analysis of Indacaterol/Glycopyrronium/Mometasone Furoate and estimate the effect of covariates on their pharmacokinetics in patients with asthma, published in the European Journal of Drug Metabolism and Pharmacokinetics.

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