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Acute Effects of Sodium GlucOse Co-Transporter 2 (SGLT2) Inhibition on Hepatic Glucose and Energy Metabolism

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Trial Profile

Acute Effects of Sodium GlucOse Co-Transporter 2 (SGLT2) Inhibition on Hepatic Glucose and Energy Metabolism

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Dapagliflozin (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Pharmacodynamics

    • Most Recent Events

    • 14 Dec 2020 Results investigating the impact of a single dose of dapagliflozin (D) or placebo (P) on hepatic glycogenolysis, hepatocellular lipid (HCL) content and mitochondrial activity (kATP), published in the Diabetes Care.
    • 25 Sep 2020 Results investigating the impact of a single dose of dapagliflozin (D) or placebo (P) on hepatic glycogenolysis, lipid content (HCL) and mitochondrial activity ( k ATP) presented at the 56th Annual Meeting of the European Association for the Study of Diabetes
    • 26 Sep 2016 Planned End Date changed from 1 Nov 2017 to 1 Jun 2018.

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