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A Phase II Pharmacodynamic Investigation of the Efficacy of Vorinostat to Induce Fetal Hemoglobin in Adults With Severe Sickle Cell Disease Who Have Not Benefitted From Prior Therapy

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Trial Profile

A Phase II Pharmacodynamic Investigation of the Efficacy of Vorinostat to Induce Fetal Hemoglobin in Adults With Severe Sickle Cell Disease Who Have Not Benefitted From Prior Therapy

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 11 May 2022

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At a glance

  • Drugs Vorinostat (Primary)
  • Indications Sickle cell anaemia
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 21 Jun 2017 Status changed from completed to discontinued early due to slow accrual.
  • 07 Oct 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
  • 07 Oct 2015 New trial record

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