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A Phase I, Single and Multiple Dose Escalation/Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, Food Effect, and Preliminary Antitumor Activities of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor

Trial Profile

A Phase I, Single and Multiple Dose Escalation/Expansion Study to Investigate the Safety, Tolerability, Pharmacokinetics, Food Effect, and Preliminary Antitumor Activities of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Oct 2024

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At a glance

  • Drugs Lifirafenib (Primary)
  • Indications Malignant melanoma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors BeiGene
  • Most Recent Events

    • 24 May 2019 Status changed from active, no longer recruiting to completed.
    • 20 Aug 2018 Status changed from recruiting to active, no longer recruiting.
    • 02 Mar 2017 Data will be presented at the 2017 American Association for Cancer Research Annual Meeting, and the company expects a decision in the first quarter of 2017 from its partner Merck KGaA on its continuation option to develop and commercialize BGB-283 outside China after Mercks review of this data, according to a BeiGene, Ltd. media release.

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