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An International, Multi-Center, Open-Label, Randomized, Phase III Trial of Sacituzumab Govitecan Versus Treatment of Physician Choice in Patients With Metastatic Triple-Negative Breast Cancer Who Received at Least Two Prior Treatments

Trial Profile

An International, Multi-Center, Open-Label, Randomized, Phase III Trial of Sacituzumab Govitecan Versus Treatment of Physician Choice in Patients With Metastatic Triple-Negative Breast Cancer Who Received at Least Two Prior Treatments

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 17 Mar 2025

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At a glance

  • Drugs Sacituzumab govitecan (Primary) ; Capecitabine; Eribulin; Gemcitabine; Vinorelbine
  • Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer; Triple negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ASCENT
  • Sponsors Gilead Sciences; Immunomedics

Most Recent Events

  • 09 Dec 2023 Results of pooled analysis from TROPiCS-02, IMMU-132-01, and ASCENT presented at the 46th Annual San Antonio Breast Cancer Symposium.
  • 09 Nov 2022 Results(n=479) assessing Health Utilities Associated With Sacituzumab Govitecan (SG) for Treating Unresectable Locally Advanced or Metastatic Triple-Negative Breast Cancer presented at the 25th Annual European Congress of the International Society for Pharmacoeconomics and Outcomes Research
  • 18 Oct 2022 Results (n=419) of an analysis assessing health-related quality of life published in the European Journal of Cancer

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