Trial Profile

AflacST1502: A Phase II Study of Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 10 Mar 2026

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At a glance

Drugs Celecoxib (Primary) ; Cyclophosphamide (Primary) ; Etoposide (Primary) ; Sirolimus (Primary)
Indications Carcinoma; Choroid neoplasms; CNS cancer; Diffuse intrinsic pontine glioma; Glioma; Histiocytosis; Medulloblastoma; Neuroepithelial neoplasms; Rhabdoid tumour; Solid tumours; Teratoma
Focus Therapeutic Use
Acronyms AflacST1502

Most Recent Events

02 Mar 2026 Planned End Date changed from 1 Jan 2026 to 1 Jun 2026.
02 Mar 2026 Planned primary completion date changed from 1 Jan 2026 to 1 Jun 2026.
27 Feb 2025 Planned End Date changed from 1 Feb 2025 to 1 Jan 2026.

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