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A Phase 1, Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of Orally Administered CA-170 in Patients With Advanced Tumors and Lymphomas

Trial Profile

A Phase 1, Open-Label, Dose Escalation and Dose Expansion Trial Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Effects of Orally Administered CA-170 in Patients With Advanced Tumors and Lymphomas

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs CA 170 (Primary)
  • Indications Lymphoma; Malignant-mesothelioma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors Curis

Most Recent Events

  • 24 Jun 2020 Status changed from active, no longer recruiting to completed.
  • 05 Nov 2019 According to a Curis media release, the company does not intend to to enroll additional patients in this study. The Company plans to further evaluate the translational science and clinical pharmacodynamics of CA-170, in addition to patient data from this study, to assess the potential of future clinical studies of CA-170.
  • 05 Nov 2019 According to a Curis media release, results from this study were presented at the Society for Immunotherapy of Cancer (SITC) 2019 Annual Meeting.

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