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Phase I Study of MK-3475 (Pembrolizumab) in Patients With Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant Neoplasm

Trial Profile

Phase I Study of MK-3475 (Pembrolizumab) in Patients With Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant Neoplasm

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Feb 2025

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At a glance

  • Drugs Pembrolizumab (Primary)
  • Indications Hodgkin's disease; Kaposi's sarcoma; Liver cancer; Malignant melanoma; Non-Hodgkin's lymphoma; Non-small cell lung cancer; Skin cancer; Solid tumours
  • Focus Adverse reactions
  • Most Recent Events

    • 08 Aug 2024 Status changed from active, no longer recruiting to completed.
    • 16 Jul 2024 Timeframe for primary measures changed from 'Up to 90 days after the last dose of trial treatment' to 'Up to 90 days after the last dose of trial treatment, up to 2 years or 35 cycles of trial treatment.'
    • 24 Oct 2023 Results from the expanded Kaposi's-sarcoma cohort (n=32) presented at the 48th European Society for Medical Oncology Congress.

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