Trial Profile

Phase I Dose-Escalation Bioavailability Study of Oral Triapine in Combination With Concurrent Chemoradiation for Locally Advanced Cervical Cancer (LACC) and Vaginal Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 08 Aug 2025

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At a glance

Drugs Cisplatin (Primary) ; OCX 191 (Primary) ; OCX 191 (Primary)
Indications Adenocarcinoma; Adenosquamous carcinoma; Cervical cancer; Squamous cell cancer; Vaginal intraepithelial neoplasia; Vulvar intraepithelial neoplasia
Focus Adverse reactions; Pharmacokinetics

Most Recent Events

15 May 2025 Planned End Date changed from 29 Apr 2025 to 29 Apr 2026.
16 Oct 2024 Planned End Date changed from 26 Nov 2024 to 29 Apr 2025.
28 Nov 2023 Planned End Date changed from 31 Dec 2023 to 26 Nov 2024.

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