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Double Blind, Randomized, Placebo-Controlled, Phase 2A Mechanistic Study to Evaluate the Effect of ISIS 449884 (ISIS-GCGRRx) on Hepatic Lipid and Glycogen Content in Patients With Type 2 Diabetes Being Treated With Metformin

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Double Blind, Randomized, Placebo-Controlled, Phase 2A Mechanistic Study to Evaluate the Effect of ISIS 449884 (ISIS-GCGRRx) on Hepatic Lipid and Glycogen Content in Patients With Type 2 Diabetes Being Treated With Metformin

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Feb 2019

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At a glance

  • Drugs IONIS-GCGRRx (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
  • Sponsors Ionis Pharmaceuticals

    • Most Recent Events

    • 14 Feb 2019 Results evaluating the safety and efficacy of IONIS-GCGRRx from three phase 2 (NCT01885260, NCT02583919, NCT02824003) published in the Diabetes Care.
    • 04 May 2018 Status changed from active, no longer recruiting to completed.
    • 17 Oct 2016 Status changed from recruiting to active, no longer recruiting.

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