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A Phase 1/2, Randomized, Single-Blind, Placebo-Controlled, Single-Ascending and Multiple-Ascending Dose, Safety, Tolerability, Pharmacokinetics, and Antiviral Efficacy Study of Subcutaneously Administered ALN-HBV in Healthy Adult Subjects and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection

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A Phase 1/2, Randomized, Single-Blind, Placebo-Controlled, Single-Ascending and Multiple-Ascending Dose, Safety, Tolerability, Pharmacokinetics, and Antiviral Efficacy Study of Subcutaneously Administered ALN-HBV in Healthy Adult Subjects and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 13 Jun 2023

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At a glance

  • Drugs ALN HBV (Primary)
  • Indications Hepatitis B
  • Focus Adverse reactions; First in man
  • Sponsors Alnylam Pharmaceuticals

    • Most Recent Events

    • 06 Jun 2023 Results from two clinical studies: NCT02826018 and NCT03672188 published in the Journal of Hepatology
    • 03 Nov 2017 Status changed from active, no longer recruiting to discontinued.
    • 04 Aug 2017 Status changed from recruiting to active, no longer recruiting.

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