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A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects With Decompensated Non-Alcoholic Steatohepatitis (NASH) Cirrhosis

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Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects With Decompensated Non-Alcoholic Steatohepatitis (NASH) Cirrhosis

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Emricasan (Primary)
  • Indications Non-alcoholic steatohepatitis; Portal hypertension
  • Focus Registrational; Therapeutic Use
  • Acronyms ENCORE-LF
  • Sponsors Conatus Pharmaceuticals

    • Most Recent Events

    • 07 Oct 2020 Results published in the Journal of Hepatology
    • 24 Jun 2019 According to a Conatus Pharmaceuticals media release, this trial did not meet primary endpoint, so the company is discontinuing further treatment of patients enrolled in this study.
    • 24 Jun 2019 Status changed from active, no longer recruiting to discontinued, according to a Conatus Pharmaceuticals media release.

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