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A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial of Emricasan (IDN-6556-12), an Oral Caspase Inhibitor, in Subjects With Non-alcoholic Steatohepatitis (NASH) Fibrosis

Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial of Emricasan (IDN-6556-12), an Oral Caspase Inhibitor, in Subjects With Non-alcoholic Steatohepatitis (NASH) Fibrosis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Emricasan (Primary)
  • Indications Hepatic fibrosis; Non-alcoholic steatohepatitis
  • Focus Therapeutic Use
  • Acronyms ENCORE-NF
  • Sponsors Conatus Pharmaceuticals

Most Recent Events

  • 27 Dec 2019 Results published in the Journal of Hepatology
  • 02 May 2019 Primary endpoint has not been met. (Fibrosis improvement by at least one stage without worsening of steatohepatitis), according to a Conatus Pharmaceuticals media release.
  • 21 Mar 2019 Status changed from active, no longer recruiting to completed, according to a Conatus Pharmaceuticals media release.

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