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A Phase Ib, Open-Label Study Evaluating the Safety and Pharmacokinetics of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Trastuzumab Emtansine or With Trastuzumab and Pertuzumab (With and Without Docetaxel) in Patients With HER2-Positive Breast Cancer and Atezolizumab With Doxorubicin and Cyclophosphamide in HER2-Negative Breast Cancer

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A Phase Ib, Open-Label Study Evaluating the Safety and Pharmacokinetics of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Trastuzumab Emtansine or With Trastuzumab and Pertuzumab (With and Without Docetaxel) in Patients With HER2-Positive Breast Cancer and Atezolizumab With Doxorubicin and Cyclophosphamide in HER2-Negative Breast Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Atezolizumab (Primary) ; Carboplatin; Cyclophosphamide; Docetaxel; Doxorubicin; Pertuzumab; Trastuzumab; Trastuzumab emtansine
  • Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer; HER2 positive breast cancer
  • Focus Adverse reactions
  • Sponsors Roche

    • Most Recent Events

    • 31 Jan 2020 Status changed from active, no longer recruiting to completed.
    • 16 Dec 2019 Planned End Date changed from 12 Dec 2019 to 9 Jan 2020.
    • 16 Dec 2019 Planned primary completion date changed from 12 Dec 2019 to 9 Jan 2020.

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