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An Open Label Trial of Dianhydrogalactitol (VAL-083) and Radiation Therapy in Treatment of Newly Diagnosed GBM Patients With An Unmethylated Promoter of the Methylguanine-DNA Methyltransferase (MGMT) Gene

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An Open Label Trial of Dianhydrogalactitol (VAL-083) and Radiation Therapy in Treatment of Newly Diagnosed GBM Patients With An Unmethylated Promoter of the Methylguanine-DNA Methyltransferase (MGMT) Gene

Status: Suspended
Phase of Trial: Phase II

Latest Information Update: 24 Nov 2023

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At a glance

  • Drugs Dianhydrogalactitol (Primary)
  • Indications Glioblastoma
  • Focus Biomarker; Therapeutic Use
  • Sponsors Del Mar Pharmaceuticals; Kintara Therapeutics

    • Most Recent Events

    • 20 Nov 2023 Planned End Date changed from 1 Sep 2022 to 30 Dec 2023.
    • 31 Oct 2023 Status changed from active, no longer recruiting to suspended, according to Kintara Therapeutics media release.
    • 31 Oct 2023 According to a Kintara Therapeutics media release, company is suspending the development of VAL-083 based on the topline preliminary safety results from GBM AGILE trial.

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