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A Phase II Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor-Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

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Trial Profile

A Phase II Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor-Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Jun 2026

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At a glance

  • Drugs Lifileucel (Primary) ; Pembrolizumab (Primary) ; Aldesleukin; Cyclophosphamide; Fludarabine; Mesna
  • Indications Malignant melanoma
  • Focus Therapeutic Use

Most Recent Events

  • 08 Jun 2026 Planned number of patients changed from 170 to 53.
  • 05 Mar 2025 Planned End Date changed from 16 Jun 2026 to 16 Jun 2028.
  • 05 Mar 2025 Planned primary completion date changed from 16 Jun 2025 to 16 Jun 2028.

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