A three arms prospective, randomized phase II study to evaluate the best sequential approach with combo immunotherapy (ipilimumab/nivolumab) and combo target therapy (LGX818/MEK162) in patients with metastatic melanoma and BRAF mutation
Latest Information Update: 11 Nov 2024
At a glance
- Drugs Binimetinib (Primary) ; Encorafenib (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary)
- Indications Malignant melanoma
- Focus Therapeutic Use
- Acronyms SECOMBIT
Most Recent Events
- 05 Nov 2024 According to a Nucleai media release, abstract in collaboration with Dr. Paolo Ascertio and Lunaphore, a Bio-Techne brand, examines the spatial proteomic profile of melanoma patients undergoing immunotherapy as part of the SECOMBIT trial will be presented at the Society for Immunotherapy of Cancer (SITC) 2024 Annual Meeting.
- 14 Jun 2024 This trial has been Discontinued in Austria, according to European Clinical Trials Database record.
- 06 Jun 2024 Status changed from active, no longer recruiting to completed.