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A Phase I, Open-Label, Non-randomised, Single Centre Study of the Absorption, Metabolism, Excretion and Pharmacokinetics of AZD2014 After a Single Oral Dose of [14C]AZD2014, Followed by Multiple Doses of AZD2014 Either As Monotherapy or In Combination With Either Fulvestrant or Paclitaxel in Patients With Advanced Solid Malignancies

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A Phase I, Open-Label, Non-randomised, Single Centre Study of the Absorption, Metabolism, Excretion and Pharmacokinetics of AZD2014 After a Single Oral Dose of [14C]AZD2014, Followed by Multiple Doses of AZD2014 Either As Monotherapy or In Combination With Either Fulvestrant or Paclitaxel in Patients With Advanced Solid Malignancies

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 06 Nov 2021

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At a glance

  • Drugs Vistusertib (Primary) ; Fulvestrant; Paclitaxel
  • Indications Adenocarcinoma; Advanced breast cancer; Endometrial cancer; Peritoneal cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 27 Jul 2017 Status changed from active, no longer recruiting to completed.
    • 12 Jan 2017 Planned End Date changed from 1 Mar 2017 to 1 Feb 2018.
    • 17 Oct 2016 Status changed from recruiting to active, no longer recruiting.

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